TSHR 420 Human Recombinant Protein

Background/Introduction: Thyroid stimulating hormone receptor (TSHR), also known as Thyrotropin receptor is a member of the leucine-rich repeat-containing G protein-coupled receptors. G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. They mediate the effects of several endogenous cues and serve as important pharmacological targets. TSHR is primarily found on the surface of the thyroid epithelial cells. Both TSHR and its ligand TSH have evolved to acquire specificity, minimize cross-reaction to other glycoprotein hormone receptors, and modulate cognate interaction (and thereby thyrotropic activity).

Small volumes of TSHR 420 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355810 is a recombinant protein targeting TSHR 420. Also known as Thyroid stimulating hormone receptor 420, TSHR420 Protein (Active). Reactive in Human.