Mouse Anti-fFN Monoclonal Antibody – Cat# MBS355828

fFN Antibody – Mouse Monoclonal

Name: fFN Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS355828
Price: 590 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS355828

Fetal fibronectin (fFN) is a fibronectin protein produced by fetal cells. It is found at the interface of the chorion and the decidua (between the fetal sac and the uterine lining). It can be thought of as an adhesive or "biological glue" that binds the fetal… More details

$590 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

fFN, Monoclonal Antibody

Full Product Name

Monoclonal Anti- Fetal Fibronectin, fFN (Capture Ab)

Product Gene Name

anti-fFN antibody

Product Synonym Names

Fetal Fibronectin mAb (Mouse anti-human, clone # 1E5)-Capture Ab

Clonality

Monoclonal

Isotype

IgG1

Clone Number

1E5

Host

Mouse

Species Reactivity

Human

Form/Format

Liquid; Supplied in 0.01 M PBS (pH7.4) without preservative.

Purity/Purification

Purity: >95% by HPLC & SDS-PAGE
Purification: Protein A or G purified

Preparation and Storage

Aliquot and store at -20°C for long term.
Avoid repeated freeze and thaw cycles

OMIM

AJ276395 mRNA

3D Structure

ModBase 3D Structure for P02751

Immunogen

Native fetal fibronectin protein

Matched Pair

Capture Ab: fFN mAb (clone # 1E5)
Detection Ab: fFN mAb (clone # A7)
It is recommended to use #1E5 & #A7 pair for Lateral flow assay (rapid test).

Applications Tested/Suitable for anti-fFN antibody

ELISA (EIA), Chemiluminescence Immunoassays (CLIA), Lateral Flow Assay (LFA) (Rapid Test)

Application Notes for anti-fFN antibody

Other applications have not been tested. The optimal dilutions should be determined by end user.

Product References and Citations for anti-fFN antibody

1. Lockwood CJ, Senyei AE, Dische MR, et al. (1991). "Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery". N. Engl. J. Med. 325 (10): 669-74.

Other Notes

Small volumes of anti-fFN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for fFN purchase

MBS355828 is an antibody targeting fFN. Also known as Monoclonal Anti- Fetal Fibronectin, fFN (Capture Ab). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for fFN. It may not necessarily be applicable to this product.

NCBI GI #

807066342

NCBI GeneID

2335

NCBI Accession #

NP_001293058.1

UniProt Primary Accession #

P02751

UniProt Secondary Accession #

O95609; O95610; Q14312; Q14325; Q14326; Q17RV7; Q564H7; Q585T2; B7ZLF0; E9PE77; E9PG29

UniProt Related Accession #

P02751

GenBank Nucleotide #

NM_001306129.1

NCBI Official Full Name

fibronectin isoform 8

NCBI Official Synonym Full Names

fibronectin 1

NCBI Official Symbol

FN1

NCBI Official Synonym Symbols

FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF

UniProt Protein Name

Fibronectin

UniProt Synonym Protein Names

Cold-insoluble globulin; CIG

UniProt Gene Name

FN1

UniProt Synonym Gene Names

FN; FN; CIG

NCBI Protein Information

fibronectin

NCBI Summary for fFN

This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016]

UniProt Comments for fFN

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.

Research Articles on fFN

1. analysis of FN in breast cancer reveals its role and diagnostic potential

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-fFN antibody

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Diseases associated with anti-fFN antibody

Disease Name	Pubmed Publications
Carcinoma Antibodies	>110 publications with fFN and Carcinoma
Fibrosis Antibodies	>50 publications with fFN and Fibrosis
Inflammation Antibodies	>37 publications with fFN and Inflammation
Breast Neoplasms Antibodies	>29 publications with fFN and Breast Neoplasms
Lung Neoplasms Antibodies	>29 publications with fFN and Lung Neoplasms
Cardiovascular Diseases Antibodies	>27 publications with fFN and Cardiovascular Diseases
Neoplasm Invasiveness Antibodies	>25 publications with fFN and Neoplasm Invasiveness
Kidney Diseases Antibodies	>25 publications with fFN and Kidney Diseases
Neoplasms, Experimental Antibodies	>23 publications with fFN and Neoplasms, Experimental
Liver Diseases Antibodies	>21 publications with fFN and Liver Diseases

Organs/Tissues associated with anti-fFN antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>69 publications with fFN and Blood
Muscle Antibodies	>47 publications with fFN and Muscle
Lung Antibodies	>46 publications with fFN and Lung
Liver Antibodies	>43 publications with fFN and Liver
Bone Antibodies	>43 publications with fFN and Bone
Vascular Antibodies	>39 publications with fFN and Vascular
Kidney Antibodies	>39 publications with fFN and Kidney
Connective Tissue Antibodies	>34 publications with fFN and Connective Tissue
Embryonic Tissue Antibodies	>26 publications with fFN and Embryonic Tissue
Thyroid Antibodies	>24 publications with fFN and Thyroid