Cancer Antigen CA15-3 Antibody – Mouse Monoclonal

CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. It is derived from MUC1. CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased chance of early recurrence in breast cancer. Both CA 15-3 and CA 27-29 may be elevated in patients with benign ovarian cysts, benign breast disease, and benign liver disease. Elevations may also be seen in cirrhosis, sarcoidosis and lupus.

1. Duffy MJ, Duggan C, Keane R, et al. (March 2004). "High preoperative CA 15-3 concentrations predict adverse outcome in node-negative and node-positive breast cancer: study of 600 patients with histologically confirmed breast cancer". Clin. Chem. 50 (3): 559–63.
2. Bearz A, Talamini R, Vaccher E, et al. (2007). "MUC-1 (CA 15-3 antigen) as a highly reliable predictor of response to EGFR inhibitors in patients with bronchioloalveolar carcinoma: an experience on 26 patients". Int. J. Biol. Markers. 22 (4): 307–11.

Small volumes of anti-Cancer Antigen CA15-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS355911 is an antibody targeting Cancer Antigen CA15-3. Also known as Monoclonal Anti-Cancer Antigen CA15-3 (Detection Ab). Reactive in Human. Host: Mouse.