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INT-767

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600005

INT-767 is a potent, selective, dual farnesoid X receptor (FXR) and TGR5 agonist with EC50 of 30 and 630 nM, respectively. More details

$595 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INT-767, Biochemical
Full Product Name
INT-767
Product Synonym Names
INT767
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
494.6601
Suitability
DMSO: >=205.5mg/mL
Target
FXR
Receptor
FXR
Chemical Name
24-Norcholane-3, 7, 23-triol, 6-ethyl-, 23-(hydrogen sulfate), sodium salt(1:1), (3alpha, 5beta, 6alpha, 7alpha)
SMILES
O[C@@H]1CC[C@@]2(C)[C@@]([C@@H](CC)[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@H](C)CCOS(=O)([O-])=O)[H])([H])C1.[Na+]
Molecular Formula
C25H43NaO6S
CAS Number
1000403-03-1

Product Categories/Family for INT-767 biochemical

Fibrosis; Metabolic Enzyme/Protease; Other Indications

Structure of INT-767 biochemical

INT-767 Biochemical – Cat# MBS3600005

Product References and Citations for INT-767 biochemical

1. Rizzo G, et al. Mol Pharmacol. 2010 Oct; 78 (4):617-30.
2. Baghdasaryan A, et al. Hepatology. 2011 Oct; 54 (4):1303-1.
3. McMahan RH, et al. J Biol Chem. 2013 Apr 26; 288 (17):11761-70.
4. Wang XX, et al. J Biol Chem. 2017 Jul 21; 292 (29):12018-12024.

Other Notes

Small volumes of INT-767 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INT-767 purchase

MBS3600005 is a biochemical targeting INT-767.
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