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MK-8033

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600025

MK-8033 is a potent, specific, dual c-Met/Ron kinases inhibitor with IC50 of 1/7 nM. More details

$370 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-8033, Biochemical
Full Product Name
MK-8033
Product Synonym Names
MK 8033; MK8033
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
471.53
Suitability
DMSO: >=46mg/mL
Target
c-Met/HGFR
Receptor
c-Met/HGFR
Chemical Name
5H-Benzo[4, 5]cyclohepta[1, 2-b]pyridine-7-methanesulfonamide, 3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-N-(2-pyridinylmethyl)
SMILES
O=S(CC1=CC=C2C(C(C3=CC(C4=CN(C)N=C4)=CN=C3C=C2)=O)=C1)(NCC5=NC=CC=C5)=O
Molecular Formula
C25H21N5O3S
CAS Number
1001917-37-8

Product Categories/Family for MK-8033 biochemical

Solid Tumors; Angiogenesis; Cancer

Structure of MK-8033 biochemical

Mk-8033 Biochemical – Cat# MBS3600025

Product References and Citations for MK-8033 biochemical

1. Northrup AB, et al. J Med Chem. 2013 Mar 28; 56 (6):2294-310.
2. Bhardwaj V, et al. J Thorac Oncol. 2012 Aug; 7 (8):1211-7.
3. Marchion DC, et al. Oncol Rep. 2013 May; 29 (5):2011-8.
4. Keedy VL, et al. Invest New Drugs. 2018 Jan 29. doi: 10.1007/s10637-018-0567-z.

Other Notes

Small volumes of MK-8033 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-8033 purchase

MBS3600025 is a biochemical targeting MK-8033.
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