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AZD-4818

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600031

AZD-4818 is a highly potent, selective CCR1 antagonist with pIC50 of 8.6, inhibits chemotaxia of human monocytes to MIP-1alpha in a concentration-dependent manner. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD-4818, Biochemical
Full Product Name
AZD-4818
Product Synonym Names
AZD4818
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
567.46
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
2-[2-Chloro-5-[(2S)-3-(5-chlorospiro[benzofuran-2(3H), 4'-piperidin]-1'-yl)-2-hydroxypropoxy]-4-[(methylamino)carbonyl]phenoxy]-2-methylpropanoic acid
SMILES
CC(C)(C(=O)O)Oc1cc(c(cc1Cl)C(=O)NC)OC[C@H](CN2CCC3(CC2)Cc4cc(ccc4O3)Cl)O
Molecular Formula
C27H32Cl2N2O7
CAS Number
1003566-93-5

Product Categories/Family for AZD-4818 biochemical

COPD; GPCR/G Protein; Inflammation/Immunology

Structure of AZD-4818 biochemical

AZD-4818 Biochemical – Cat# MBS3600031

Product References and Citations for AZD-4818 biochemical

1. Kerstjens HA, et al. Respir Med. 2010 Sep; 104 (9):1297-303.
2. Norman P. Expert Opin Ther Pat. 2009 Nov; 19 (11):1629-33.
3. Gilchrist A, et al. Br J Pharmacol. 2014 Nov; 171 (22):5127-38.

Other Notes

Small volumes of AZD-4818 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD-4818 purchase

MBS3600031 is a biochemical targeting AZD-4818.
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