• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MK-5108

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600067

MK-5108 (VX-689) is a potent, highly selective Aurora-A kinase inhibitor with IC50 of 0.064 nM. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-5108, Biochemical
Full Product Name
MK-5108
Product Synonym Names
MK 5108; VX-689; VX 689; MK5108; VX689
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
461.94
Suitability
DMSO: 6.4mg/mL Need warming
Target
Aurora Kinase
Receptor
AuroraA
Chemical Name
Cyclohexanecarboxylic acid, 4-(3-chloro-2-fluorophenoxy)-1-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-, trans
SMILES
OC(=O)[C@@]1(CC2=CC=CC(NC3=NC=CS3)=N2)CC[C@@H](CC1)OC1=C(F)C(Cl)=CC=C1|r,c:7,13,16,26,30,32,t:5,11|
Molecular Formula
C22H21ClFN3O3S
CAS Number
1010085-13-8

Product Categories/Family for MK-5108 biochemical

Solid Tumors; Cell Cycle/DNA Damage; Cancer

Structure of MK-5108 biochemical

Mk-5108 Biochemical – Cat# MBS3600067

Product References and Citations for MK-5108 biochemical

1. Shimomura T, et al. Mol Cancer Ther. 2010 Jan; 9 (1):157-66.
2. Kretzner L, et al. Cancer Res. 2011 Jun 1; 71 (11):3912-20.
3. Shan W, et al. Clin Cancer Res. 2012 Jun 15; 18 (12):3352-65.
4. Chefetz I, et al. Cell Cycle. 2011 Jul 1; 10 (13):2206-14.

Other Notes

Small volumes of MK-5108 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-5108 purchase

MBS3600067 is a biochemical targeting MK-5108.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000