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VTP-27999 2, 2, 2-trifluoroacetate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600079

MBS3600079 is a biochemical targeting VTP-27999 2, 2, 2-trifluoroacetate. A potent, highly selective renin inhibitor with IC50 of 0.47 nM. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VTP-27999 2, 2, 2-trifluoroacetate, Biochemical
Full Product Name
VTP-27999 2, 2, 2-trifluoroacetate
Product Synonym Names
VTP 27999, 2, 2, 2-trifluoroacetate; VTP27999
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
639.1039
Suitability
10mM in DMSO
Target
Renin
Receptor
Renin
Chemical Name
Carbamic acid, N-[2-[(R)-(3-chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]-, methyl ester, 2, 2, 2-trifluoroacetate(1:1)
SMILES
O=C(OC)NCCO[C@@H](C1=CC=CC(Cl)=C1)[C@H]2CN(C(NC[C@@H](NC)C[C@@H]3COCCC3)=O)CCC2.O=C(O)C(F)(F)F
Molecular Formula
C28H42ClF3N4O7
CAS Number
1013937-63-7

Product Categories/Family for VTP-27999 2, 2, 2-trifluoroacetate biochemical

Hypertension; Metabolic Enzyme/Protease; Cardiovascular Disease

Structure of VTP-27999 2, 2, 2-trifluoroacetate biochemical

VTP-27999 2, 2, 2-trifluoroacetate Biochemical – Cat# MBS3600079

Product References and Citations for VTP-27999 2, 2, 2-trifluoroacetate biochemical

1. Jia L, et al. ACS Med Chem Lett. 2011 Aug 9; 2 (10):747-51.
2. Krop M, et al. Hypertension. 2013 May; 61 (5):1075-82.
3. Balcarek J, et al. Hypertension. 2014 May; 63 (5):942-50.

Other Notes

Small volumes of VTP-27999 2, 2, 2-trifluoroacetate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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