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SGX-523

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600105

SGX-523 is a potent, selective ATP-competitive inhibitor of MET receptor tyrosine kinase with IC50 of 4 nM. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SGX-523, Biochemical
Full Product Name
SGX-523
Product Synonym Names
SGX523; SGX 523
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
359.4077
Suitability
DMSO: >=3.6mg/mL
Target
c-Met/HGFR
Receptor
Abl; B-Raf (V599E); c-Met; C-Raf; p38alpha
Chemical Name
Quinoline, 6-[[6-(1-methyl-1H-pyrazol-4-yl)-1, 2, 4-triazolo[4, 3-b]pyridazin-3-yl]thio]
SMILES
CN1N=CC(C2=NN3C(C=C2)=NN=C3SC4=CC=C5N=CC=CC5=C4)=C1
Molecular Formula
C18H13N7S
CAS Number
1022150-57-7

Product Categories/Family for SGX-523 biochemical

Solid Tumors; Angiogenesis; Cancer

Structure of SGX-523 biochemical

SGX-523 Biochemical – Cat# MBS3600105

Product References and Citations for SGX-523 biochemical

1. Buchanan SG, et al. Mol Cancer Ther. 2009 Dec; 8 (12):3181-90.
2. Guessous F, et al. Anticancer Agents Med Chem. 2010 Jan; 10 (1):28-35.
3. Zhang YW, et al. Cancer Res. 2010 Sep 1; 70 (17):6880-90.
4. Xie Q, et al. Proc Natl Acad Sci U S A. 2012 Jan 10; 109 (2):570-5.

Other Notes

Small volumes of SGX-523 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SGX-523 purchase

MBS3600105 is a biochemical targeting SGX-523.
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