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Fostamatinib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600119

Fostamatinib (R788 disodium salt) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fostamatinib, Biochemical
Full Product Name
Fostamatinib
Product Synonym Names
R788 disodium salt; R935788
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
624.4232
Suitability
10mM in DMSO
Target
Syk
Receptor
Syk
Chemical Name
2H-Pyrido[3, 2-b]-1, 4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3, 4, 5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2, 2-dimethyl-4-[(phosphonooxy)methyl]-, sodium salt(1:2)
SMILES
[Na+].[Na+].COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP([O-])([O-])=O)C=C3)=N2)=CC(OC)=C1OC
Molecular Formula
C23H24FN6Na2O9P
CAS Number
1025687-58-4

Product Categories/Family for Fostamatinib biochemical

Rheumatoid Arthritis; Angiogenesis; Inflammation/Immunology

Structure of Fostamatinib biochemical

Fostamatinib Biochemical – Cat# MBS3600119

Product References and Citations for Fostamatinib biochemical

1. Braselmann S, et al. J Pharmacol Exp Ther. 2006 Dec; 319 (3):998-1008.
2. Chen L, et al. Blood. 2008 Feb 15; 111 (4):2230-7.
3. Suljagic M, et al. Blood. 2010 Dec 2; 116 (23):4894-905.

Other Notes

Small volumes of Fostamatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fostamatinib purchase

MBS3600119 is a biochemical targeting Fostamatinib.
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