Pexidartinib (PLX-3397)

Name: Pexidartinib (PLX-3397); MyBioSource
Brand: MyBioSource
SKU: MBS3600138
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600138

An oral-active, BBB-penatrant, potent mutil-targeted RTK inhibitor of CSF-1R, Kit, and Flt3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Pexidartinib, Biochemical

Full Product Name

Pexidartinib

Product Synonym Names

PLX-3397; PLX3397

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

417.8148

Suitability

DMSO: >=30mg/mL

Target

CSF1R

Receptor

CSF-1R; FLT3; Kit

Chemical Name

3-Pyridinemethanamine, N-[5-[(5-chloro-1H-pyrrolo[2, 3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)

SMILES

FC(F)(F)C1=NC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C34)C=C2)C=C1

Molecular Formula

C20H15ClF3N5

CAS Number

1029044-16-3

Product Categories/Family for Pexidartinib biochemical

Skin Cancer; Tyrosine Kinase; Cancer

Product References and Citations for Pexidartinib biochemical

1. DeNardo DG, et al. Cancer Discov. 2011 Jun; 1 (1):54-67.
2. Coniglio SJ, et al. Mol Med. 2012 May 9; 18:519-27.
3. Chitu V, et al. Blood. 2012 Oct 11; 120 (15):3126-35.

Other Notes

Small volumes of Pexidartinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Pexidartinib purchase

MBS3600138 is a biochemical targeting Pexidartinib.