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GNE-493

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600163

A potent, selective dual pan-PI3K/mTOR inhibitor with IC50 of 3.4/12/16/16/32 nM for PI3Kalpha/PI3Kbeta/PI3Kgamma/PI3Kdelta/mTOR. More details

$275 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-493, Biochemical
Full Product Name
GNE-493
Product Synonym Names
GNE493; GNE 493
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
372.4447
Suitability
DMSO: >=45mg/mL
Target
PI3K
Receptor
PI3K
Chemical Name
Thieno[3, 2-d]pyrimidine-6-methanol, 2-(2-amino-5-pyrimidinyl)-alpha, alpha-dimethyl-4-(4-morpholinyl)
SMILES
CC(O)(C1=CC2=NC(C3=CN=C(N)N=C3)=NC(N4CCOCC4)=C2S1)C
Molecular Formula
C17H20N6O2S
CAS Number
1033735-94-2

Product Categories/Family for GNE-493 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of GNE-493 biochemical

GNE-493 Biochemical – Cat# MBS3600163

Product References and Citations for GNE-493 biochemical

1. Sutherlin DP, et al. J Med Chem. 2010 Feb 11; 53 (3):1086-97.

Other Notes

Small volumes of GNE-493 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNE-493 purchase

MBS3600163 is a biochemical targeting GNE-493.
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