Saridegib (Patidegib)

Name: Saridegib (Patidegib); MyBioSource
Brand: MyBioSource
SKU: MBS3600185
Price: 1610 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600185

Saridegib (Patidegib, IPI-926) is a potent and orally active Hedgehog (Hh) pathway antagonist with IC50 of 7 nM. More details

$1610 / 5 mg +2 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Saridegib, Biochemical

Full Product Name

Saridegib

Product Synonym Names

Patidegib; IPI-926

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

504.768

Target

Smoothened (Smo)

Receptor

Smoothened (Smo)

Chemical Name

N-((2S, 3R, 3aS, 3'R, 4a'R, 6S, 6a'R, 6b'S, 7aR, 12a'S, 12b'S)-3, 6, 11', 12b'-tetramethyl-2', 3a, 3', 4, 4', 4a', 5, 5', 6, 6', 6a', 6b', 7, 7a, 7', 8', 10', 12', 12a', 12b'-icosahydro-1'H, 3H-spiro[furo[3, 2-b]pyridine-2, 9'-naphtho[2, 1-a]azulen]-3'-yl)methanesulfonamide

SMILES

CS(=O)(N[C@H](CC[C@@]12C)C[C@@]1([H])CC[C@]3([H])[C@]2([H])CC4=C(C)C[C@@](O5)(CC[C@@]34[H])[C@H](C)[C@@]6([H])[C@@]5([H])C[C@H](C)CN6)=O

Molecular Formula

C29H48N2O3S

CAS Number

1037210-93-7

Product Categories/Family for Saridegib biochemical

Pancreatic Cancer; Wnt/Notch/Hedgehog; Cancer

Product References and Citations for Saridegib biochemical

1. Olive KP, et al. Science. 2009 Jun 12; 324 (5933):1457-61.
2. Tremblay MR, et al. J Med Chem. 2009 Jul 23; 52 (14):4400-18.
3. Lee MJ, et al. Proc Natl Acad Sci U S A. 2012 May 15; 109 (20):7859-64.

Other Notes

Small volumes of Saridegib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Saridegib purchase

MBS3600185 is a biochemical targeting Saridegib.