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R428 (BGB324)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600189

MBS3600189 is a biochemical targeting R428. R428 (BGB324) is an inhibitor of Axl with IC50 of 14 nM. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
R428, Biochemical
Full Product Name
R428
Product Synonym Names
BGB324
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
506.64
Suitability
DMSO: 24mg/mL warmed (47.37mM)
Ethanol: <1mg/mL (<1mM)
Water: <1mg/mL (<1mM)
Target
TAM Receptor
Receptor
AXL
Chemical Name
(S)-1-(6, 7-dihydro-5H-benzo[6, 7]cyclohepta[1, 2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)-6, 7, 8, 9-tetrahydro-5H-benzo[7]annulen-2-yl)-1H-1, 2, 4-triazole-3, 5-diamine
SMILES
NC1=NC(NC2=CC=C3C(CC[C@@H](N4CCCC4)CC3)=C2)=NN1C5=NN=C6C(CCCC7=CC=CC=C76)=C5
Molecular Formula
C30H34N8
CAS Number
1037624-75-1

Product Categories/Family for R428 biochemical

Tyrosine Kinase; Cancer

Structure of R428 biochemical

R428 BGB324 Biochemical – Cat# MBS3600189

Product References and Citations for R428 biochemical

1.Holland SJ, et al. Cancer Res, 2010, 70 (4), 1544-1554.

Other Notes

Small volumes of R428 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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