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Fosdagrocorat (PF 04171327)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600220

Fosdagrocorat (PF 04171327) is an orally available, potential dissociated agonist of the glucocorticoid receptor (GR) for the treatment of rheumatoid arthritis. More details

$470 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fosdagrocorat, Biochemical
Full Product Name
Fosdagrocorat
Product Synonym Names
PF 04171327
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
574.537
Target
GR
Receptor
GR
Chemical Name
(2R, 4aS, 10aR)-4a-benzyl-7-((2-methylpyridin-3-yl)carbamoyl)-2-(trifluoromethyl)-1, 2, 3, 4, 4a, 9, 10, 10a-octahydrophenanthren-2-yl dihydrogen phosphate
SMILES
O=P(O)(O[C@@]1(C(F)(F)F)C[C@@]2([H])CCC3=C(C=CC(C(NC4=CC=CN=C4C)=O)=C3)[C@]2(CC5=CC=CC=C5)CC1)O
Molecular Formula
C29H30F3N2O5P
CAS Number
1044535-58-1

Product References and Citations for Fosdagrocorat biochemical

1. Stock T, et al. Int J Rheum Dis. 2017 Aug; 20 (8):960-970.
2. Miyoshi S, et al. Int J Clin Pharmacol Ther. 2016 Dec; 54 (12):966-976.
3. Ripp SL, et al. Clin Pharmacol Drug Dev. 2017 Nov 7. doi: 10.1002/cpdd.411.

Other Notes

Small volumes of Fosdagrocorat biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Fosdagrocorat purchase

MBS3600220 is a biochemical targeting Fosdagrocorat.
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