Dolutegravir Sodium (GSK-1349572A)

Name: Dolutegravir Sodium (GSK-1349572A); MyBioSource
Brand: MyBioSource
SKU: MBS3600249
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600249

Dolutegravir sodium (GSK-1349572A) is a potent, next-generation HIV integrase (IN) inhibitor, inhibits HIV-1 integrase-catalyzed strand transfer with IC50 of 2.7 nM. More details

$235 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dolutegravir sodium, Biochemical

Full Product Name

Dolutegravir sodium

Product Synonym Names

GSK-1349572A

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

441.3606

Suitability

DMSO: >=4.4mg/mL
DMSO: <12.6mg/mL

Target

HIV

Receptor

HIVintegrase

Chemical Name

2H-Pyrido[1', 2':4, 5]pyrazino[2, 1-b][1, 3]oxazine-9-carboxamide, N-[(2, 4-difluorophenyl)methyl]-3, 4, 6, 8, 12, 12a-hexahydro-7-hydroxy-4-methyl-6, 8-dioxo-, sodium salt(1:1), (4R, 12aS)

SMILES

C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

Molecular Formula

C20H18F2N3NaO5

CAS Number

1051375-19-9

Product Categories/Family for Dolutegravir sodium biochemical

HIV Infection; Microbiology/Virology; Infection

Product References and Citations for Dolutegravir sodium biochemical

1. Kobayashi M, et al. Antimicrob Agents Chemother. 2011 Feb; 55 (2):813-21.
2. Garrido C, et al. Antiviral Res. 2011 Jun; 90 (3):164-7.
3. Hightower KE, et al. Antimicrob Agents Chemother. 2011 Oct; 55 (10):4552-9.
4. Hare S, et al. Mol Pharmacol. 2011 Oct; 80 (4):565-72.

Other Notes

Small volumes of Dolutegravir sodium biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dolutegravir sodium purchase

MBS3600249 is a biochemical targeting Dolutegravir sodium.