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PF-03715455

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600256

PF-03715455 is a highly potent and selective inhibitor for p38alpha MAPK with IC50 of 1.6 nM. More details

$1460 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-03715455, Biochemical
Full Product Name
PF-03715455
Product Synonym Names
PF03715455
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
700.273
Target
p38 MAPK
Receptor
p38 MAPK
Chemical Name
1-(3-(tert-butyl)-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl)-3-(2-((3-(2-((2-hydroxyethyl)thio)phenyl)-[1, 2, 4]triazolo[4, 3-a]pyridin-6-yl)thio)benzyl)urea
SMILES
CC(C)(C)C1=NN(C(=C1)NC(=O)NCC2=CC=CC=C2SC3=CN4C(=NN=C4C5=CC=CC=C5SCCO)C=C3)C6=CC(=C(C=C6)O)Cl
Molecular Formula
C35H34ClN7O3S2
CAS Number
1056164-52-3

Product Categories/Family for PF-03715455 biochemical

COPD; MAPK/ERK Signaling; Inflammation/Immunology

Structure of PF-03715455 biochemical

Pf-03715455 Biochemical – Cat# MBS3600256

Product References and Citations for PF-03715455 biochemical

1. Millan DS, et al. J Med Chem. 2011 Nov 24; 54 (22):7797-814.
2. Singh D, et al. Eur J Clin Pharmacol. 2015 Oct; 71 (10):1175-84.

Other Notes

Small volumes of PF-03715455 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-03715455 purchase

MBS3600256 is a biochemical targeting PF-03715455.
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