• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

WYE-354

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600274

WYE-354 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 5 nM (recombinant mTOR ). More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WYE-354, Biochemical
Full Product Name
WYE-354
Product Synonym Names
WYE 354; WYE354
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
495.5309
Suitability
DMSO: >=26mg/mL
Target
mTOR
Receptor
GCK; Hck; mTOR; PI3Kalpha; PI3Kgamma
Chemical Name
1-Piperidinecarboxylic acid, 4-[6-[4-[(methoxycarbonyl)amino]phenyl]-4-(4-morpholinyl)-1H-pyrazolo[3, 4-d]pyrimidin-1-yl]-, methyl ester
SMILES
O=C(N1CCC(N2N=CC3=C(N4CCOCC4)N=C(C5=CC=C(NC(OC)=O)C=C5)N=C32)CC1)OC
Molecular Formula
C24H29N7O5
CAS Number
1062169-56-5

Product Categories/Family for WYE-354 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of WYE-354 biochemical

WYE-354 Biochemical – Cat# MBS3600274

Product References and Citations for WYE-354 biochemical

1. Yu K, et al. Cancer Res. 2009 Aug 1; 69 (15):6232-40.
2. Wahdan-Alaswad RS, et al. Mol Cancer Res. 2012 Jun; 10 (6):821-33.
3. Weber H, et al. Oncotarget. 2015 Oct 13; 6 (31):31877-88.
4. Liu Q, et al. J Biol Chem. 2012 Mar 23; 287 (13):9742-52.

Other Notes

Small volumes of WYE-354 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WYE-354 purchase

MBS3600274 is a biochemical targeting WYE-354.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000