LDN193189

Name: Ldn193189; MyBioSource
Brand: MyBioSource
SKU: MBS3600276
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600276

LDN193189 is a potent, selective BMP type I receptor that inhibits BMP4-induced phosphorylation of SMAD1/5/8 with IC50 of 5 nM. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LDN193189, Biochemical

Full Product Name

LDN193189

Product Synonym Names

LDN 193189; LDN-193189; DM-3189

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

406.4824

Suitability

Ethanol: 0.25mg/mL, Need ultrasonic and warming
DMSO: <0.1mg/mL
H2O: <0.1mg/mL

Target

ALK

Receptor

ALK2; ALK3

Chemical Name

Quinoline, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1, 5-a]pyrimidin-3-yl]

SMILES

C1CN(CCN1)C1=CC=C(C=C1)C1=CN2N=CC(=C2N=C1)C1=CC=NC2=CC=CC=C12

Molecular Formula

C25H22N6

CAS Number

1062368-24-4

Product Categories/Family for LDN193189 biochemical

Angiogenesis; Cancer

Product References and Citations for LDN193189 biochemical

1. Yu PB, et al. Nat Med. 2008 Dec; 14 (12):1363-9.
2. Cuny GD, et al. Bioorg Med Chem Lett. 2008 Aug 1; 18 (15):4388-92.
3. Cannon JE, et al. Br J Pharmacol. 2010 Sep; 161 (1):140-9.
4. Steinbicker AU, et al. Blood. 2011 May 5; 117 (18):4915-23.

Other Notes

Small volumes of LDN193189 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS3600276 is a biochemical targeting LDN193189.

LDN193189

Product Overview

Product Categories/Family for LDN193189 biochemical

Structure of LDN193189 biochemical

Related Product Information for LDN193189 biochemical

Product References and Citations for LDN193189 biochemical

Other Notes

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