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Calicheamicin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600324

Calicheamicin gamma1 is an enediyne antitumor antibiotic that acts by binding to DNA and causes strand scission; ADC payload used in development of antibody drug conjugates. More details

$615 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Calicheamicin, Biochemical
Full Product Name
Calicheamicin
Product Synonym Names
Calicheamicin gamma1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1368.348
Suitability
10mM in DMSO
Target
ADC Cytotoxin
Receptor
ADC Cytotoxin
Chemical Name
Carbamic acid, N-[(1R, 4Z, 8S, 13E)-8-[[4, 6-dideoxy-4-[[[2, 6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-alpha-L-mannopyranosyl)oxy]-3-iodo-5, 6-dimethoxy-2-methylbenzoyl]-4-thio-beta-D-ribo-hexopyranosyl]oxy]amino]-2-O-[2, 4-dideoxy-4-(ethylamino)-3-O-methyl-alpha-L-threo-pento
SMILES
O=C(S[C@@H]1[C@@H](C)O[C@@H](ON[C@@H]2[C@@H](C)OC(O[C@@H](C#C/C=CC#C[C@@]3(O)C4)C(/C3=CCSSSC)=C(NC(OC)=O)C4=O)[C@H](O[C@H]5C[C@H](OC)[C@@H](NCC)CO5)[C@H]2O)C[C@@H]1O)C6=C(OC)C(OC)=C(O[C@H]7[C@H](O)[C@H](OC)[C@@H](O)[C@H](C)O7)C(I)=C6C
Molecular Formula
C55H74IN3O21S4
CAS Number
108212-75-5

Product Categories/Family for Calicheamicin biochemical

Antibody Drug Conjugates (ADC); Cancer

Structure of Calicheamicin biochemical

Calicheamicin Biochemical – Cat# MBS3600324

Product References and Citations for Calicheamicin biochemical

1. Lambert JM, et al. Adv Ther. 2017 May; 34 (5):1015-1035.
2. Guffroy M, et al. Clin Cancer Res. 2017 Apr 1; 23 (7):1760-1770.
3. Damelin M, et al. Clin Cancer Res. 2015 Sep 15; 21 (18):4165-73.

Other Notes

Small volumes of Calicheamicin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Calicheamicin purchase

MBS3600324 is a biochemical targeting Calicheamicin.
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