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N-Acetyl-Calicheamicin

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600325

N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission. More details

$1120 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
N-Acetyl-Calicheamicin, Biochemical
Full Product Name
N-Acetyl-Calicheamicin
Product Synonym Names
N-Acetyl-Calicheamicin gamma; N-Acetyl-gamma-calicheamicin
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1410.385
Suitability
10mM in DMSO
Target
Antibacterial
Receptor
Antibacterial
Chemical Name
Carbamic acid, [(1R, 4Z, 8S, 13E)-8-[[2-O-[4-(acetylethylamino)-2, 4-dideoxy-3-O-methyl-alpha-L-threo-pentopyranosyl]-4, 6-dideoxy-4-[[[2, 6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-alpha-L-mannopyranosyl)oxy]-3-iodo-5, 6-dimethoxy-2-methylbenzoyl]-4-thio-beta-D-ribo-hexopyrano
SMILES
CCN(C1COC(CC1OC)OC2C(C(C(OC2OC3C#CC=CC#CC4(CC(=O)C(=C3C4=CCSSSC)NC(=O)OC)O)C)NOC5CC(C(C(O5)C)SC(=O)C6=C(C(=C(C(=C6OC)OC)OC7C(C(C(C(O7)C)O)OC)O)I)C)O)O)C(=O)C
Molecular Formula
C57H76IN3O22S4
CAS Number
108212-76-6

Product References and Citations for N-Acetyl-Calicheamicin biochemical

1. Stasi R, et al. Cancer Treat Rev. 2008 Feb; 34 (1):49-60.
2. Naito K, et al. Leukemia. 2000 Aug; 14 (8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug; 15 (9):986-96.

Other Notes

Small volumes of N-Acetyl-Calicheamicin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS3600325 is a biochemical targeting N-Acetyl-Calicheamicin.
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