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GSK-923295

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600340

The first potent, allosteric inhibitor of CENP-E kinesin motor ATPase activity with Ki of 3.2 nM. More details

$265 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK-923295, Biochemical
Full Product Name
GSK-923295
Product Synonym Names
GSK 923295; GSK923295
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
592.1282
Suitability
10mM in DMSO
Target
Kinesin
Receptor
CENP-E
Chemical Name
Benzamide, 3-chloro-N-[(1S)-2-[[2-(dimethylamino)acetyl]amino]-1-[[4-[8-[(1S)-1-hydroxyethyl]imidazo[1, 2-a]pyridin-2-yl]phenyl]methyl]ethyl]-4-(1-methylethoxy)
SMILES
O=C(N[C@@H](CC1=CC=C(C2=CN3C=CC=C([C@@H](O)C)C3=N2)C=C1)CNC(CN(C)C)=O)C4=CC=C(OC(C)C)C(Cl)=C4
Molecular Formula
C32H38ClN5O4
CAS Number
1088965-37-0

Product Categories/Family for GSK-923295 biochemical

Solid Tumors; Cytoskeleton/Cell Adhesion Molecules; Cancer

Structure of GSK-923295 biochemical

GSK-923295 Biochemical – Cat# MBS3600340

Product References and Citations for GSK-923295 biochemical

1. Wood KW, et al. Proc Natl Acad Sci U S A. 2010 Mar 30; 107 (13):5839-44.
2. Qian X, et al. ACS Med Chem Lett. 2010 Jan 19; 1 (1):30-4.
3. Balamuth NJ, et al. Cancer Res. 2010 Apr 1; 70 (7):2749-58.

Other Notes

Small volumes of GSK-923295 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK-923295 purchase

MBS3600340 is a biochemical targeting GSK-923295.
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