Poziotinib (HM781-36B)

Name: Poziotinib (HM781-36B); MyBioSource
Brand: MyBioSource
SKU: MBS3600347
Price: 250 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600347

Poziotinib (HM781-36B, NOV120101) is an irreversible pan-HER inhibitor with IC50 of 3.2/5.3 nM/23.5 nM for HER1/HER2/HER4. More details

$250 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Poziotinib, Biochemical

Full Product Name

Poziotinib

Product Synonym Names

HM781-36B; NOV120101

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

491.3423

Suitability

10mM in DMSO

Target

EGFR

Receptor

HER1; HER2; HER4

Chemical Name

2-Propen-1-one, 1-[4-[[4-[(3, 4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]

SMILES

C=CC(N1CCC(OC2=CC3=C(NC4=CC=C(Cl)C(Cl)=C4F)N=CN=C3C=C2OC)CC1)=O

Molecular Formula

C23H21Cl2FN4O3

CAS Number

1092364-38-9

Product Categories/Family for Poziotinib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Poziotinib biochemical

1. Nam HJ, et al. Cancer Lett. 2011 Mar 28; 302 (2):155-65.
2. Cha MY, et al. Int J Cancer. 2012 May 15; 130 (10):2445-54.
3. Kim HJ, et al. Anticancer Drugs. 2012 Mar; 23 (3):288-97.

Other Notes

Small volumes of Poziotinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Poziotinib purchase

MBS3600347 is a biochemical targeting Poziotinib.