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SCH-1473759

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600365

A potent, picomolar, dual inhibitor of Aurora A and B with IC50 of 0.02 and 0.03 nM, respectively; shows improved cell potency (phos-HH3 inhibition IC50=25 nM) and intrinsic aqueous solubility (11.4 mM). More details

$345 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCH-1473759, Biochemical
Full Product Name
SCH-1473759
Product Synonym Names
SCH1473759; SCH 1473759
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
426.5385
Suitability
10mM in DMSO
Target
Aurora Kinase
Receptor
Aurora Kinase
Chemical Name
1-Propanol, 2-[ethyl[[5-[[6-methyl-3-(1H-pyrazol-4-yl)imidazo[1, 2-a]pyrazin-8-yl]amino]-3-isothiazolyl]methyl]amino]-2-methyl
SMILES
CC(C)(N(CC)CC1=NSC(NC2=NC(C)=CN3C2=NC=C3C4=CNN=C4)=C1)CO
Molecular Formula
C20H26N8OS
CAS Number
1094069-99-4

Product Categories/Family for SCH-1473759 biochemical

Cell Cycle/DNA Damage; Cancer

Structure of SCH-1473759 biochemical

SCH-1473759 Biochemical – Cat# MBS3600365

Product References and Citations for SCH-1473759 biochemical

1. Yu T, et al. ACS Med Chem Lett. 2010 Jun 7; 1 (5):214-8.
2. Basso AD, et al. Cancer Chemother Pharmacol. 2011 Oct; 68 (4):923-33.

Other Notes

Small volumes of SCH-1473759 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCH-1473759 purchase

MBS3600365 is a biochemical targeting SCH-1473759.
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