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GSK1838705A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600424

GSK1838705A is a potent, specific inhibitor of IGF-IR and insulin receptor (IR) with IC50 of 2.0 and 1.6 nM. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK1838705A, Biochemical
Full Product Name
GSK1838705A
Product Synonym Names
GSK 1838705A; GSK-1838705A
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
532.5693
Suitability
10mM in DMSO
Target
ALK
Receptor
ALK; IGF-1R; InsulinReceptor; JNK3; RSK1
Chemical Name
Benzamide, 2-[[2-[[1-[2-(dimethylamino)acetyl]-2, 3-dihydro-5-methoxy-1H-indol-6-yl]amino]-7H-pyrrolo[2, 3-d]pyrimidin-4-yl]amino]-6-fluoro-N-methyl
SMILES
O=C(NC)C1=C(F)C=CC=C1NC2=C3C(NC=C3)=NC(NC4=CC5=C(C=C4OC)CCN5C(CN(C)C)=O)=N2
Molecular Formula
C27H29FN8O3
CAS Number
1116235-97-2

Product Categories/Family for GSK1838705A biochemical

Angiogenesis; Cancer

Structure of GSK1838705A biochemical

GSK1838705A Biochemical – Cat# MBS3600424

Product References and Citations for GSK1838705A biochemical

1. Sabbatini P, et al. Mol Cancer Ther. 2009 Oct; 8 (10):2811-20.
2. Zhou F, et al. Onco Targets Ther. 2015 Apr 10; 8:753-60.
3. Refolomg, et al. Oncotarget. 2017 Sep 30; 8 (61):103465-103476.
4. Kelleher FC, et al. Eur J Cancer. 2010 Sep; 46 (13):2357-68.

Other Notes

Small volumes of GSK1838705A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK1838705A purchase

MBS3600424 is a biochemical targeting GSK1838705A.
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