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JNJ-40411813

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600446

MBS3600446 is a biochemical targeting JNJ-40411813. A novel potent positive allosteric modulator of mGlu2 with EC50 of 147 nM. More details

$285 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JNJ-40411813, Biochemical
Full Product Name
JNJ-40411813
Product Synonym Names
JNJ40411813; ADX 71149
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
344.883
Suitability
DMSO: 25mg/mL (72.49mM)
Target
mGluR
Receptor
mGluR
Chemical Name
1-butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)-pyridone
SMILES
ClC1=C(N2CCC(C3=CC=CC=C3)CC2)C=CN(CCCC)C1=O
Molecular Formula
C20H25ClN2O
CAS Number
1127498-03-6

Product Categories/Family for JNJ-40411813 biochemical

Epilepsy; GPCR/G Protein; Neurological Disease

Structure of JNJ-40411813 biochemical

JNJ-40411813 Biochemical – Cat# MBS3600446

Product References and Citations for JNJ-40411813 biochemical

1. Cid JM, et al. J Med Chem. 2014 Aug 14; 57 (15):6495-512.
2. Ahnaou A, et al. Neuropharmacology. 2016 Apr; 103:290-305.
3. Lavreysen H, et al. Pharmacol Res Perspect. 2015 Mar; 3 (2):e00097.
4. Kent JM, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jun 3; 67:66-73.

Other Notes

Small volumes of JNJ-40411813 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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