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MK-0249

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600571

MK-0249 is a novel potent, selective histamine H3 inverse agonist for the treatment of cognitive impairment with schizophrenia. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-0249, Biochemical
Full Product Name
MK-0249
Product Synonym Names
MK0249
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
431.459
Target
Histamine Receptor
Receptor
Histamine Receptor
Chemical Name
2-methyl-3-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)-5-(trifluoromethyl)quinazolin-4(3H)-one
SMILES
O=C1N(C2=CC=C(OCCCN3CCCC3)C=C2)C(C)=NC4=C1C(C(F)(F)F)=CC=C4
Molecular Formula
C23H24F3N3O2
CAS Number
1167574-41-5

Product Categories/Family for MK-0249 biochemical

Sleep Disorder; GPCR/G Protein; Neurological Disease

Structure of MK-0249 biochemical

Mk-0249 Biochemical – Cat# MBS3600571

Product References and Citations for MK-0249 biochemical

1. Brioni JD, et al. J Pharmacol Exp Ther. 2011 Jan; 336 (1):38-46.
2. James LM, et al. Psychopharmacology (Berl). 2011 Jun; 215 (4):643-53.
3. Zoethout RW, et al. J Psychopharmacol. 2012 Feb; 26 (2):292-302.

Other Notes

Small volumes of MK-0249 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0249 purchase

MBS3600571 is a biochemical targeting MK-0249.
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