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U0126 (U0126-EtOH)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600579

U0126 (U0126-EtOH) is a potent, selective MEK (MAP2K) inhibitor with IC50 of 70 nM and 60 nM for MEK1 and MEK2. More details

$215 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
U0126, Biochemical
Full Product Name
U0126
Product Synonym Names
U0126-EtOH; U 0126; U-0126
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
426.5583
Suitability
DMSO: >=49mg/mL
Target
MEK
Receptor
CDK2; CDK4; MEK1; MEK2; PKC
Chemical Name
Butanedinitrile, 2, 3-bis[amino[(2-aminophenyl)thio]methylene]-, compd. with ethanol(1:1)
SMILES
CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N
Molecular Formula
C20H22N6OS2
CAS Number
1173097-76-1

Product Categories/Family for U0126 biochemical

Structure of U0126 biochemical

U0126-EtOH Biochemical – Cat# MBS3600579

Product References and Citations for U0126 biochemical

1. Favata MF, et al. J Biol Chem. 1998 Jul 17; 273 (29):18623-32.
2. DeSilva DR, et al. J Immunol. 1998 May 1; 160 (9):4175-81.
3. Bessard A, et al. Oncogene. 2008 Sep 11; 27 (40):5315-25.
4. Duncia JV, et al. Bioorg Med Chem Lett. 1998 Oct 20; 8 (20):2839-44.

Other Notes

Small volumes of U0126 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for U0126 purchase

MBS3600579 is a biochemical targeting U0126.
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