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Rivipansel Sodium (GMI-1070)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600649

Rivipansel sodium (GMI-1070, PF-06460031) is a novel small molecule glycomimetic pan-Selectin antagonist with IC50 of 4.3 uM, 423 uM and 337 uM for E-selectin, P-selectin and L-selectin, respectively. More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Rivipansel sodium, Biochemical
Full Product Name
Rivipansel sodium
Product Synonym Names
GMI-1070; PF-06460031
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Target
Selectin
Receptor
Selectin
Chemical Name
(S)-2-(((2R, 3R, 4S, 5S, 6R)-3-(benzoyloxy)-2-(((1R, 2R, 3S, 5R)-3-(2, 6-dioxo-1, 2, 3, 6-tetrahydropyrimidine-4-carboxamido)-5-((2-(2-(2-(2-oxo-2-((3, 6, 8-trisulfonaphthalen-1-yl)amino)ethoxy)ethoxy)acetamido)ethyl)carbamoyl)-2-(((2S, 3S, 4R, 5S, 6S)-3, 4, 5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)cyclohexyl)oxy)-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-3-cyclohexylpropanoic acid
SMILES
CC1C(C(C(C(O1)OC2C(CC(CC2OC3C(C(C(C(O3)CO)O)OC(CC4CCCCC4)C(=O)[O-])OC(=O)C5=CC=CC=C5)C(=O)NCCNC(=O)COCCOCC(=O)NC6=C7C(=CC(=C6)S(=O)(=O)[O-])C=C(C=C7S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C8=CC(=O)NC(=O)N8)O)O)O.[Na+].[Na+].[Na+].[Na+]
Molecular Formula
C58H74N6O31S3
CAS Number
1189037-60-2

Product References and Citations for Rivipansel sodium biochemical

1. Chang J, et al. Blood. 2010 Sep 9; 116 (10):1779-86.
2. Azab AK, et al. Blood. 2012 Feb 9; 119 (6):1468-78.
3. Wun T, et al. PLoS One. 2014 Jul 2; 9 (7):e101301.

Other Notes

Small volumes of Rivipansel sodium biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rivipansel sodium purchase

MBS3600649 is a biochemical targeting Rivipansel sodium.
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