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MK-4618

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600653

A potent and selective full beta3 adrenergic receptor agonist with EC50 of 1.1 nM; displays no activity for beta1 and beta2 receptors (EC50>20 uM). More details

$700 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-4618, Biochemical
Full Product Name
MK-4618
Product Synonym Names
MK 4618; MK4618; Vibegron; KRP-114V; RVT-901
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
444.535
Target
Adrenergic Receptor
Receptor
Adrenergic Receptor
Chemical Name
(S)-N-(4-(((2S, 5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4, 6, 7, 8-tetrahydropyrrolo[1, 2-a]pyrimidine-6-carboxamide
SMILES
O=C([C@@H]1CCC2=NC=CC(N21)=O)NC3=CC=C(C[C@H]4N[C@@H]([C@H](O)C5=CC=CC=C5)CC4)C=C3
Molecular Formula
C26H28N4O3
CAS Number
1190389-15-1

Product Categories/Family for MK-4618 biochemical

Other Disease; Angiogenesis; Other Indications

Structure of MK-4618 biochemical

Mk-4618 Biochemical – Cat# MBS3600653

Product References and Citations for MK-4618 biochemical

1. Edmondson SD, et al. J Med Chem. 2016 Jan 28; 59 (2):609-23.
2. Di Salvo J, et al. J Pharmacol Exp Ther. 2017 Feb; 360 (2):346-355.

Other Notes

Small volumes of MK-4618 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-4618 purchase

MBS3600653 is a biochemical targeting MK-4618.
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