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Cipargamin (KAE609)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600671

Cipargamin (KAE609, NITD609) is a fast-acting, potent antimalarial agent that inhibits blood-stage activity in vitro against a panel of culture-adapted P. falciparum strains with IC50 of 0.5-1.4 nM. More details

$260 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cipargamin, Biochemical
Full Product Name
Cipargamin
Product Synonym Names
KAE609; NITD609
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
390.239
Suitability
DMSO: 50mg/mL (128.13mM)
H2O: <0.1mg/mL
Target
Parasite
Receptor
Parasite
Chemical Name
(1'R, 3'S)-5, 7'-Dichloro-6'-fluoro-2', 3', 4', 9'-tetrahydro-3'-methylspiro[3H-indole-3, 1'-[1H]pyrido[3, 4-b]indol]-2(1H)-one
SMILES
O=C([C@]12N[C@@H](C)CC3=C1NC4=C3C=C(F)C(Cl)=C4)NC5=C2C=C(Cl)C=C5
Molecular Formula
C19H14Cl2FN3O
CAS Number
1193314-23-6

Product References and Citations for Cipargamin biochemical

1. Rottmann M, et al. Science. 2010 Sep 3; 329 (5996):1175-80.
2. van Pelt-Koops JC, et al. Antimicrob Agents Chemother. 2012 Jul; 56 (7):3544-8.
3. Spillman NJ, et al. Cell Host Microbe. 2013 Feb 13; 13 (2):227-37.
4. Zhou Y, et al. Antimicrob Agents Chemother. 2014; 58 (3):1789-92.

Other Notes

Small volumes of Cipargamin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cipargamin purchase

MBS3600671 is a biochemical targeting Cipargamin.
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