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LY2811376

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600676

A potent, orally available non-peptidic beta-secretase (BACE1) inhibitor with IC50 of 239 nM in enzyme assays. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY2811376, Biochemical
Full Product Name
LY2811376
Product Synonym Names
LY 2811376; LY-2811376
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
320.3603
Suitability
DMSO: >=31mg/mL
Target
BACE
Receptor
Abeta; BACE1
Chemical Name
4H-1, 3-Thiazin-2-amine, 4-[2, 4-difluoro-5-(5-pyrimidinyl)phenyl]-5, 6-dihydro-4-methyl-, (4S)
SMILES
NC1=N[C@](C)(C2=CC(C3=CN=CN=C3)=C(F)C=C2F)CCS1
Molecular Formula
C15H14F2N4S
CAS Number
1194044-20-6

Product Categories/Family for LY2811376 biochemical

Alzheimer Disease; Metabolic Enzyme/Protease; Neurological Disease

Structure of LY2811376 biochemical

LY2811376 Biochemical – Cat# MBS3600676

Product References and Citations for LY2811376 biochemical

1. May PC, et al. J Neurosci. 2011 Nov 16; 31 (46):16507-16.
2. Filser S, et al. Biol Psychiatry. 2015 Apr 15; 77 (8):729-39.
3. Portelius E, et al. Alzheimers Res Ther. 2014 Nov 17; 6 (5-8):75.
4. Cheret C, et al. EMBO J. 2013 Jul 17; 32 (14):2015-28.

Other Notes

Small volumes of LY2811376 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2811376 purchase

MBS3600676 is a biochemical targeting LY2811376.
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