Dabrafenib (GSK2118436)

Name: Dabrafenib (GSK2118436); MyBioSource
Brand: MyBioSource
SKU: MBS3600687
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600687

Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dabrafenib, Biochemical

Full Product Name

Dabrafenib

Product Synonym Names

GSK2118436

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20°C
Stability: ≥2 years

Molecular Weight

519.56

Suitability

DMSO: 30mg/mL (57.74mM)

Target

Raf

Receptor

B-Raf; B-Raf (V600E); C-Raf

SMILES

CC(C)(C)C1=NC(=C(S1)C1=NC(N)=NC=C1)C1=C(F)C(NS(=O)(=O)C2=C(F)C=CC=C2F)=CC=C1

Molecular Formula

C23H20F3N5O2S2

CAS Number

1195765-45-7

Product Categories/Family for Dabrafenib biochemical

MAPK/ERK Signaling; Cancer

Product References and Citations for Dabrafenib biochemical

1.Sylvie Laquerre, et al. 2009, EORTC International Conference. Abst B88.

Other Notes

Small volumes of Dabrafenib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Dabrafenib purchase

MBS3600687 is a biochemical targeting Dabrafenib.