GDC-0575 (ARRY-575)

Name: GDC-0575 (ARRY-575); MyBioSource
Brand: MyBioSource
SKU: MBS3600694
Price: 285 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600694

GDC-0575 (ARRY-575, RG-7741) is a potent, selective and orally bioavailable Chk1 inhibitor with IC50 of 1.2 nM. More details

$285 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GDC-0575, Biochemical

Full Product Name

GDC-0575

Product Synonym Names

ARRY-575; RG-7741; GDC0575

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

377.286

Suitability

DMSO: >=50mg/mL (132.18mM)

Target

Chk

Receptor

Chk

Chemical Name

(R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-indol-3-yl)cyclopropanecarboxamide

SMILES

C1CC(CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N

Molecular Formula

C17H21BrN4O

CAS Number

1196541-47-5

Product Categories/Family for GDC-0575 biochemical

Blood cancer; Angiogenesis; Cancer

Product References and Citations for GDC-0575 biochemical

1. Duan W, et al. Front Oncol. 2014 Dec 19; 4:368.
2. Di Tullio A, et al. Nat Commun. 2017 Nov 22; 8 (1):1679.

Other Notes

Small volumes of GDC-0575 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0575 purchase

MBS3600694 is a biochemical targeting GDC-0575.