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GNE-220

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600715

MBS3600715 is a biochemical targeting GNE-220. GNE-220 is a potent and selective inhibitor of MAP4K4 with IC50 of 7 nM. More details

$1100 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-220, Biochemical
Full Product Name
GNE-220
Product Synonym Names
GNE220
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
438.539
Target
MAP4K
Receptor
MAP4K
Chemical Name
4-Methyl-8-[4-(4-methyl-1-piperazinyl)phenyl]-2-(1-methyl-1H-pyrazol-4-yl)-5H-pyrido[3', 2':4, 5]pyrrolo[3, 2-d]pyrimidine
SMILES
CC1=C2C(=NC(=N1)C3=CN(N=C3)C)C4=C(N2)N=CC(=C4)C5=CC=C(C=C5)N6CCN(CC6)C
Molecular Formula
C25H26N8
CAS Number
1199590-75-4

Product Categories/Family for GNE-220 biochemical

MAPK/ERK Signaling

Structure of GNE-220 biochemical

GNE-220 Biochemical – Cat# MBS3600715

Product References and Citations for GNE-220 biochemical

1. Vitorino P, et al. Nature. 2015 Mar 26; 519 (7544):425-30.
2. Gao X, et al. Cell Biosci. 2016 Oct 28; 6:56. eCollection 2016.

Other Notes

Small volumes of GNE-220 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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