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R-59949

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600724

A small molecule inhibitor of diacylglycerol kinase (DGK) with IC50 of 0.01-10 uM in isolated platelet membranes and in intact platelets. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
R-59949, Biochemical
Full Product Name
R-59949
Product Synonym Names
R59949; R 59949
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
489.585
Target
DGK
Receptor
DGK
Chemical Name
3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
SMILES
O=C1N(CCN2CC/C(CC2)=C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)C(NC5=C1C=CC=C5)=S
Molecular Formula
C28H25F2N3OS
CAS Number
120166-69-0

Product Categories/Family for R-59949 biochemical

Structure of R-59949 biochemical

R-59949 Biochemical – Cat# MBS3600724

Product References and Citations for R-59949 biochemical

1. Dominguez CL, et al. Cancer Discov. 2013 Jul; 3 (7):782-97.
2. de Chaffoy de Courcelles D, et al. J Biol Chem. 1989 Feb 25; 264 (6):3274-85.
3. Rodri­guez-Liares B, et al. Biochem Pharmacol. 1991 Mar 1; 41 (5):835-8.
4. Jiang Y, et al. Biochem Pharmacol. 2000 Apr 1; 59 (7):763-72.

Other Notes

Small volumes of R-59949 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for R-59949 purchase

MBS3600724 is a biochemical targeting R-59949.
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