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GSK2245035

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600768

GSK2245035 is a highly potent, selective TLR7 agonist that selectively induces TFN-alpha in PBMC assays with pEC50 of 9.3, >2 logs selectivity over TNFalpha pEC50. More details

$375 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK2245035, Biochemical
Full Product Name
GSK2245035
Product Synonym Names
GSK 2245035; GSK-2245035
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
390.532
Target
TLR
Receptor
TLR
Chemical Name
(S)-6-amino-2-(pentan-2-yloxy)-9-(5-(piperidin-1-yl)pentyl)-7, 9-dihydro-8H-purin-8-one
SMILES
CCCC(C)OC1=NC(=C2C(=N1)N(C(=O)N2)CCCCCN3CCCCC3)N
Molecular Formula
C20H34N6O2
CAS Number
1207629-49-9

Product Categories/Family for GSK2245035 biochemical

Asthma; Immunology/Inflammation; Inflammation/Immunology

Structure of GSK2245035 biochemical

GSK2245035 Biochemical – Cat# MBS3600768

Product References and Citations for GSK2245035 biochemical

1. Biggadike K, et al. J Med Chem. 2016 Mar 10; 59 (5):1711-26.
2. Ellis AK, et al. Clin Exp Allergy. 2017 Sep; 47 (9):1193-1203.

Other Notes

Small volumes of GSK2245035 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK2245035 purchase

MBS3600768 is a biochemical targeting GSK2245035.
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