GKT137831 (Setanaxib)

Name: Gkt137831 (Setanaxib); MyBioSource
Brand: MyBioSource
SKU: MBS3600823
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600823

GKT137831 (Setanaxib, GKT-137831) is a potent, selective, dual NADPH oxidase Nox1/4 inhibitor with Ki of 110/140 nM. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GKT137831, Biochemical

Full Product Name

GKT137831

Product Synonym Names

Setanaxib; GKT-137831

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

394.8542

Suitability

DMSO: >=37mg/mL

Target

NADPH

Receptor

NOX1; NOX4

Chemical Name

1H-Pyrazolo[4, 3-c]pyridine-3, 6(2H, 5H)-dione, 2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl

SMILES

CN(C)C1=CC(C2=C(C(N(C3=CC=CC=C3Cl)N4)=O)C4=CC(N2C)=O)=CC=C1

Molecular Formula

C21H19ClN4O2

CAS Number

1218942-37-0

Product Categories/Family for GKT137831 biochemical

Diabetes; Membrane Transporter/Ion Channel; Metabolic Disease

Product References and Citations for GKT137831 biochemical

1. Jiang JX, et al. Free Radic Biol Med. 2012 Jul 15; 53 (2):289-96.
2. Aoyama T, et al. Hepatology. 2012 Dec; 56 (6):2316-27.
3. Gray SP, et al. Circulation. 2013 May 7; 127 (18):1888-902.
4. Laleu B, et al. J Med Chem. 2010 Nov 11; 53 (21):7715-30.

Other Notes

Small volumes of GKT137831 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GKT137831 purchase

MBS3600823 is a biochemical targeting GKT137831.