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ML197 (NCGC00185963)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600847

ML197 is a potent, selective small molecule inhibitor of Cdc2-like kinases (CLK) and DYRK with IC50 of 96/40/206 nM for CLK1/CLK4/Dyrk1A, respectively. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML197, Biochemical
Full Product Name
ML197
Product Synonym Names
NCGC00185963; ML 197
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
376.434
Target
CLK
Receptor
CLK
Chemical Name
6-(benzo[d][1, 3]dioxol-5-yl)-N-((2-methylthiazol-4-yl)methyl)quinazolin-4-amine
Molecular Formula
C20H16N4O2S
CAS Number
1222891-88-4

Product Categories/Family for ML197 biochemical

Structure of ML197 biochemical

ML197 NCGC00185963 Biochemical – Cat# MBS3600847

Product References and Citations for ML197 biochemical

1. Rosenthal AS, et al. Bioorg Med Chem Lett. 2011 May 15; 21 (10):3152-8.
2. Ewton DZ, et al. Mol Cancer Ther. 2011 Nov; 10 (11):2104-14.
3. Rosenthal AS, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

Other Notes

Small volumes of ML197 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ML197 purchase

MBS3600847 is a biochemical targeting ML197.
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