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Torin1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600848

Torin1 is a highly potent, selective inhibitor of mTORC1 and mTORC2 with IC50 of 2 and 10 nM. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Torin1, Biochemical
Full Product Name
Torin1
Product Synonym Names
Torin 1; Torin-1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
607.6243
Suitability
DMSO: 6.6mg/mL (Need ultrasonic or warming)
Target
mTOR
Receptor
DNA-PK; mTOR; mTORC1; mTORC2; p110gamma
Chemical Name
Benzo[h]-1, 6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)
SMILES
O=C1N(C2=CC=C(N3CCN(C(CC)=O)CC3)C(C(F)(F)F)=C2)C4=C(C=NC5=CC=C(C6=CC7=CC=CC=C7N=C6)C=C54)C=C1
Molecular Formula
C35H28F3N5O2
CAS Number
1222998-36-8

Product Categories/Family for Torin1 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of Torin1 biochemical

Torin1 Biochemical – Cat# MBS3600848

Product References and Citations for Torin1 biochemical

1. Thoreen CC, et al. J Biol Chem. 2009 Mar 20; 284 (12):8023-32.
2. Liu Q, et al. J Med Chem. 2010 Oct 14; 53 (19):7146-55.
3. Weichhart T, et al. Blood. 2011 Apr 21; 117 (16):4273-83.
4. Thoreen CC, et al. Autophagy. 2009 Jul; 5 (5):725-6.

Other Notes

Small volumes of Torin1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Torin1 purchase

MBS3600848 is a biochemical targeting Torin1.
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