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Torin2

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600851

Torin2 is a potent, selective, orally available inhibitor of mTOR, inhibits mTORC1-dependent T389 phosphorylation on S6K with IC50 of 0.25 nM. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Torin2, Biochemical
Full Product Name
Torin2
Product Synonym Names
Torin 2; Torin-2
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
432.3973
Suitability
10mM in DMSO
Target
mTOR
Receptor
ATM; ATR; DNA-PK; mTOR
Chemical Name
Benzo[h]-1, 6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]
SMILES
O=C1N(C2=CC=CC(C(F)(F)F)=C2)C3=C(C=NC4=CC=C(C5=CC=C(N)N=C5)C=C43)C=C1
Molecular Formula
C24H15F3N4O
CAS Number
1223001-51-1

Product Categories/Family for Torin2 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of Torin2 biochemical

Torin2 Biochemical – Cat# MBS3600851

Product References and Citations for Torin2 biochemical

1. Liu Q, et al. J Med Chem. 2011 Mar 10; 54 (5):1473-80.
2. Liu Q, et al. Cancer Res. 2013 Apr 15; 73 (8):2574-86.
3. Berry T, et al. Cancer Cell. 2012 Jul 10; 22 (1):117-30.

Other Notes

Small volumes of Torin2 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Torin2 purchase

MBS3600851 is a biochemical targeting Torin2.
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