SMCC-DM1 (DM1-SMCC)

Name: SMCC-DM1 (DM1-SMCC); MyBioSource
Brand: MyBioSource
SKU: MBS3600886
Price: 300 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600886

A thioether linker conjugated with potent microtubule-disrupting agent DM1 (mertansine). More details

$300 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SMCC-DM1, Biochemical

Full Product Name

SMCC-DM1

Product Synonym Names

DM1-SMCC

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

1072.61164

Suitability

10mM in DMSO

Target

Drug-Linker Conjugates

Receptor

Drug-Linker Conjugates

Chemical Name

Maytansine, N2'-deacetyl-N2'-[3-[[1-[[4-[[(2, 5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2, 5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]

SMILES

C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=CC=C(C)CC3=CC(N(C)C(C[C@@H](OC([C@@H](N(C(CCSC(C(N4CC5CCC(C(ON6C(CCC6=O)=O)=O)CC5)=O)CC4=O)=O)C)C)=O)[C@@]7(C)C1O7)=O)=C(Cl)C(OC)=C3

Molecular Formula

C51H66ClN5O16S

CAS Number

1228105-51-8

Product Categories/Family for SMCC-DM1 biochemical

Antibody Drug Conjugates (ADC); Other Indications

Product References and Citations for SMCC-DM1 biochemical

1. Erickson HK, et al. Cancer Res. 2006 Apr 15; 66 (8):4426-33.
2. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15; 15 (12):4028-37.
3. Erickson HK, et al. Bioconjug Chem. 2010 Jan; 21 (1):84-92.
4. Kellogg BA, et al. Bioconjug Chem. 2011 Apr 20; 22 (4):717-27.

Other Notes

Small volumes of SMCC-DM1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SMCC-DM1 purchase

MBS3600886 is a biochemical targeting SMCC-DM1.