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LY2784544

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600896

LY2784544 (Gandotinib) is a potent, selective and ATP-competitive inhibitor of JAK2V617F. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY2784544, Biochemical
Full Product Name
LY2784544
Product Synonym Names
LY 2784544; LY-2784544; Gandotinib
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
469.9423
Suitability
10mM in DMSO
Target
JAK
Receptor
FLT3; JAK1; JAK2; JAK2 (V617F)
Chemical Name
Imidazo[1, 2-b]pyridazin-6-amine, 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)
SMILES
CC1=NNC(NC2=NN3C(C(CN4CCOCC4)=C2)=NC(C)=C3CC5=CC=C(Cl)C=C5F)=C1
Molecular Formula
C23H25ClFN7O
CAS Number
1229236-86-5

Product Categories/Family for LY2784544 biochemical

Blood cancer; Angiogenesis; Cancer

Structure of LY2784544 biochemical

LY2784544 Biochemical – Cat# MBS3600896

Product References and Citations for LY2784544 biochemical

1. Ma L, et al. Blood Cancer J. 2013 Apr 12; 3:e109.
2. Telford BJ, et al. Mol Cancer Ther. 2015 May; 14 (5):1213-23.
3. Gunerka P, et al. Eur J Pharmacol. 2015 Oct 15; 765:188-97.
4. Sato S, et al. Mol Pharmacol. 2016 Dec; 90 (6):726-737.

Other Notes

Small volumes of LY2784544 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2784544 purchase

MBS3600896 is a biochemical targeting LY2784544.
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