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URMC-099

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600902

URMC-099 is a potent, orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3 (MLK3) with IC50 of 14 nM. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
URMC-099, Biochemical
Full Product Name
URMC-099
Product Synonym Names
URMC099
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
421.5368
Suitability
DMSO: >=33mg/mL
Target
MLK
Receptor
Abl1; AuroraA; AuroraB; AuroraC; CDK1; CDK2; c-Met; DLK; IGF-1R; InsulinReceptor; Lck; LRRK2; MEKK2; MLK1; MLK2; MLK3; ROCK1; ROCK2; SGK; SGK1; Syk; TrkA; TrkB; VEGFR1/FLT1
Chemical Name
1H-Pyrrolo[2, 3-b]pyridine, 3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]
SMILES
CN1CCN(CC2=CC=C(C3=CN=C(NC=C4C5=CC6=C(NC=C6)C=C5)C4=C3)C=C2)CC1
Molecular Formula
C27H27N5
CAS Number
1229582-33-5

Product Categories/Family for URMC-099 biochemical

MAPK/ERK Signaling; Neurological Disease

Structure of URMC-099 biochemical

URMC-099 Biochemical – Cat# MBS3600902

Product References and Citations for URMC-099 biochemical

1. Marker DF, et al. J Neurosci. 2013 Jun 12; 33 (24):9998-10010.
2. Goodfellow VS, et al. J Med Chem. 2013 Oct 24; 56 (20):8032-48.
3. Zhang G, et al. Nanomedicine. 2016 Jan; 12 (1):109-22.
4. Polesskaya O, et al. Mol Immunol. 2014 Apr; 58 (2):214-22.

Other Notes

Small volumes of URMC-099 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for URMC-099 purchase

MBS3600902 is a biochemical targeting URMC-099.
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