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XMD8-87

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600934

XMD8-87 (Ack1 inhibitor B19) is a potent Ack1 inhibitor with Kd of 15 nM, inhibits EGF-induced autophosphorylation in HEK293 cells at 2 uM. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XMD8-87, Biochemical
Full Product Name
XMD8-87
Product Synonym Names
Ack1 inhibitor B19
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
445.527
Suitability
DMSO: 65mg/mL (145.89mM)
Ethanol: 5mg/mL (11.2mM)
Water: <1mg/mL (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Ack1 (TNK2)
Receptor
TNK2
Chemical Name
2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5, 11-dihydro-6H-benzo[e]pyrimido[5, 4-b][1, 4]diazepin-6-one
SMILES
C1=NC(NC2=CC=C(N3CCN(C)CC3)C=C2OC)=NC2N(C)C3C=CC=CC=3C(=O)NC1=2
Molecular Formula
C24H27N7O2
CAS Number
1234480-46-6

Product Categories/Family for XMD8-87 biochemical

Tyrosine Kinase; Cancer

Structure of XMD8-87 biochemical

XMD8-87 Biochemical – Cat# MBS3600934

Product References and Citations for XMD8-87 biochemical

1. Miduturu CV, et al. Chem Biol. 2011 Jul 29; 18 (7):868-79.
2. Mahajan K, et al. Cancer Lett. 2013 Sep 28; 338 (2):185-92.
3. Maxson JE, et al. Cancer Res. 2016 Jan 1; 76 (1):127-38.

Other Notes

Small volumes of XMD8-87 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XMD8-87 purchase

MBS3600934 is a biochemical targeting XMD8-87.
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