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INX-08189

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600937

A phosphoramidate prodrug of O-6-methyl-2-C-methyl guanosine, potent inhibitor of HCV NS5B polymerase with IC50 of 10 nM in replicon assay. More details

$690 / 50 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
INX-08189, Biochemical
Full Product Name
INX-08189
Product Synonym Names
INX08189; BMS-986094
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
658.649
Suitability
10mM in DMSO
Target
HCV
Receptor
HCV
Chemical Name
Neopentyl((((2R, 3R, 4R)-5-(2-amino-6-methoxy-9H-purin-9-yl)-3, 4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(naphthalen-1-yloxy)phosphoryl)-L-alaninate
SMILES
C[C@H](NP(OC1=C2C=CC=CC2=CC=C1)(OC[C@H]3O[C@@H](N4C=NC5=C(OC)N=C(N)N=C45)[C@](C)(O)[C@@H]3O)=O)C(OCC(C)(C)C)=O
Molecular Formula
C30H39N6O9P
CAS Number
1234490-83-5

Product Categories/Family for INX-08189 biochemical

HCV Infection; Microbiology/Virology; Infection

Structure of INX-08189 biochemical

INX-08189 Biochemical – Cat# MBS3600937

Product References and Citations for INX-08189 biochemical

1. McGuigan C, et al. Bioorg Med Chem Lett. 2010 Aug 15; 20 (16):4850-4.
2. Vernachio JH, et al. Antimicrob Agents Chemother. 2011 May; 55 (5):1843-51.
3. Ehteshami M, et al. Antimicrob Agents Chemother. 2016 Jul 22; 60 (8):4659-69.

Other Notes

Small volumes of INX-08189 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for INX-08189 purchase

MBS3600937 is a biochemical targeting INX-08189.
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