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A-1155463

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600940

MBS3600940 is a biochemical targeting A-1155463. A-1155463 is a highly potent and selective BCL-XL inhibitor (Ki=10 pM). More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
A-1155463, Biochemical
Full Product Name
A-1155463
Product Synonym Names
A1155463; A 1155463
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
669.7881
Suitability
DMSO: >=31mg/mL
Target
Bcl-2
Receptor
Bcl-xL; Bcl-2
Chemical Name
4-Thiazolecarboxylic acid, 2-[8-[(2-benzothiazolylamino)carbonyl]-3, 4-dihydro-2(1H)-isoquinolinyl]-5-[3-[4-[3-(dimethylamino)-1-propyn-1-yl]-2-fluorophenoxy]propyl]
SMILES
O=C(C1=C(CCCOC2=CC=C(C#CCN(C)C)C=C2F)SC(N3CC4=C(C=CC=C4C(NC5=NC6=CC=CC=C6S5)=O)CC3)=N1)O
Molecular Formula
C35H32FN5O4S2
CAS Number
1235034-55-5

Product Categories/Family for A-1155463 biochemical

Angiogenesis; Cancer

Structure of A-1155463 biochemical

A-1155463 Biochemical – Cat# MBS3600940

Product References and Citations for A-1155463 biochemical

1. Tao ZF, et al. ACS Med Chem Lett. 2014 Aug 26; 5 (10):1088-93.
2. Leverson JD, et al. Sci Transl Med. 2015 Mar 18; 7 (279):279ra40.
3. Punnoose EA, et al. Mol Cancer Ther. 2016 May; 15 (5):1132-44.

Other Notes

Small volumes of A-1155463 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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