WNT-974 (LGK-974)

Name: WNT-974 (LGK-974); MyBioSource
Brand: MyBioSource
SKU: MBS3600986
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600986

A potent and specific small-molecule Porcupine (PORCN) inhibitor with IC50 of 1 nM in the PORCN radioligand binding assay. More details

$240 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WNT-974, Biochemical

Full Product Name

WNT-974

Product Synonym Names

LGK-974; LGK974; LGK 974; WNT 974; WNT974

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

396.4445

Suitability

DMSO: >=32mg/mL

Target

Porcupine

Receptor

Porcn

Chemical Name

[2, 4'-Bipyridine]-5-acetamide, 2', 3-dimethyl-N-[5-(2-pyrazinyl)-2-pyridinyl]

SMILES

O=C(NC1=NC=C(C2=NC=CN=C2)C=C1)CC3=CN=C(C4=CC(C)=NC=C4)C(C)=C3

Molecular Formula

C23H20N6O

CAS Number

1243244-14-5

Product Categories/Family for WNT-974 biochemical

Colon Cancer; Wnt/Notch/Hedgehog; Cancer

Product References and Citations for WNT-974 biochemical

1. Liu J, et al. Proc Natl Acad Sci U S A. 2013 Dec 10; 110 (50):20224-9.
2. Jiang X, et al. Proc Natl Acad Sci U S A. 2013 Jul 30; 110 (31):12649-54.
3. Moon J, et al. Proc Natl Acad Sci U S A. 2017 Feb 14; 114 (7):1649-1654.

Other Notes

Small volumes of WNT-974 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT-974 purchase

MBS3600986 is a biochemical targeting WNT-974.