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CDK4-IN-1 (LEE011 analog)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601055

CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM. More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CDK4-IN-1, Biochemical
Full Product Name
CDK4-IN-1
Product Synonym Names
LEE011 analog; CDK4-IN-1; CDK4IN-1; CDK4-IN1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
440.97
Suitability
DMSO: 10mM
Target
CDK
Receptor
CDK4; Cyclin D1
Chemical Name
4-(3-Chloro-5-propan-2-yl-1H-pyrazol-4-yl)-N-[5-[4-(dimethylamino)piperidin-1-yl]pyridin-2-yl]pyrimidin-2-amine
SMILES
CN(C1CCN(C2=CN=C(NC3=NC=CC(C4=C(C(C)C)NN=C4Cl)=N3)C=C2)CC1)C
Molecular Formula
C22H29ClN8
CAS Number
1256963-02-6

Product Categories/Family for CDK4-IN-1 biochemical

Product References and Citations for CDK4-IN-1 biochemical

1.Cho YS, et al. J Med Chem. 2010 Nov 25; 53 (22):7938-57.

Other Notes

Small volumes of CDK4-IN-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CDK4-IN-1 purchase

MBS3601055 is a biochemical targeting CDK4-IN-1.
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