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ABT-199 (GDC-0199)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3601056

MBS3601056 is a biochemical targeting ABT-199. Venetoclax (ABT-199, GDC-0199) is a Bcl-2-selective inhibitor with Ki of More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ABT-199, Biochemical
Full Product Name
ABT-199
Product Synonym Names
GDC-0199
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
868.44
Suitability
DMSO: 100mg/mL warmed (115.14mM)
Target
Bcl-2
Receptor
Mcl-1; Bcl-2; Bcl-w; Bcl-xL
Chemical Name
4-(4-{[2-(4-chlorophenyl)-4, 4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2, 3-b]pyridin-5-yloxy)benzamide
SMILES
O=C(NS(=O)(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)CC4)C=C3OC7=CN=C(NC=C8)C8=C7
Molecular Formula
C45H50ClN7O7S
CAS Number
1257044-40-8

Product Categories/Family for ABT-199 biochemical

Angiogenesis; Cancer

Structure of ABT-199 biochemical

ABT-199 GDC-0199 Biochemical – Cat# MBS3601056

Product References and Citations for ABT-199 biochemical

1.Souers AJ, et al. Nat Med, 2013, 19 (2), 202-208.

Other Notes

Small volumes of ABT-199 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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